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近廿年来,认为血栓形成在动脉粥样硬化及其并发症的发生方面可能起有一定作用,而血小板在动脉血栓形成中占有主要地位。本文报道21例冠心病患者血小板功能的研究。病例均经选择性冠状动脉造影显示至少有一支冠状动脉主支有病变,管腔狭窄>50％。测定血小板生存时间(放射性铬)、血小板粘附性及血小板聚合性,并同时测定血胆固醇、甘油三脂、血清脂蛋白电泳。将结果与心绞痛、有无心肌梗塞、吸烟史及冠状动脉造影的发现联系起来予以评定。结果:健康者16例为对照组,男14例,女2例,年龄30～40岁,血小板生存时间平均
In the past 20 years, thrombosis is thought to play a role in the development of atherosclerosis and its complications, while platelets play a major role in arterial thrombosis. This article reports on the platelet function in 21 patients with coronary heart disease. Cases were confirmed by selective coronary angiography showed that at least one of the main coronary artery lesions, stenosis> 50%. The survival time of platelets (radioactive chromium), platelet adhesion and platelet aggregation were measured. Blood cholesterol, triglyceride and serum lipoprotein electrophoresis were measured at the same time. The results were correlated with angina, presence or absence of myocardial infarction, smoking history, and findings from coronary angiography. Results: 16 healthy people as control group, 14 males and 2 females, aged 30 to 40 years, mean platelet survival time