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AIM:To evaluate the detection and differentiation ability of contrast-enhanced intraoperative ultrasonography(CE-IOUS) in hepatocellular carcinoma(HCC) operations.METHODS:Clinical data of 50 HCC patients were retrospective analyzed.The sensitivity,specificity,false negative and false positive rates of contrast enhanced magnetic resonance imaging(CE-MRI),IOUS and CEIOUS were calculated and compared.Surgical strategy changes due to CE-IOUS were analyzed.RESULTS:Lesions detected by CE-MRI,IOUS and CEIOUS were 60,97 and 85 respectively.The sensitivity,specificity,false negative rate,false positive rate of CEMRI were 98.2%,98.6%,98.6%,60.0%,respectively;for IOUS were 50.0%,90.9%,1.8%,1.4%,respectively;and for CE-IOUS were 1.4%,40.0%,50.0%,9.1%,respectively.The operation strategy of 9(9/50,18.0%) cases was changed according to the results of CE-IOUS.CONCLUSION:Compared with CE-MRI,CE-IOUS performs better in detection and differentiation of small metastasis and regenerative nodules.It plays an important role in the decision-making of HCC operation.
AIM: To evaluate the detection and differentiation ability of contrast-enhanced intraoperative ultrasonography (CE-IOUS) in hepatocellular carcinoma (HCC) operations. METHODS: Clinical data of 50 HCC patients were retrospective analyzed. Sensitivity, specificity, false negative and false positive Rates of contrast enhanced magnetic resonance imaging (CE-MRI), IOUS and CEIOUS were calculated and compared. Surgical strategy changes due to CE-IOUS were analyzed .RESULTS: Lesions detected by CE-MRI, IOUS and CEIOUS were 60, 97 and 85 respectively.The sensitivity, specificity, false negative rate, false positive rate of CEMRI were 98.2%, 98.6%, 98.6%, 60.0%, respectively; for IOUS were 50.0%, 90.9%, 1.8%, 1.4%, respectively; and for CE-IOUS were 1.4%, 40.0%, 50.0%, 9.1% respectively. The operation strategy of 9 (9/50, 18.0%) cases was changed according to the results of CE- IOUS.CONCLUSION: Compared with CE-MRI , CE-IOUS perform better in detection and differentiation of small metastasis and regenerative nodules .It plays a n important role in the decision-making of HCC operation.