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该文回顾分析1990年1月～1995年1月间33例早产者应用硫酸镁治疗的临床资料,并与同期29例早产采用卧床加镇静剂方法作对照。结果显示:硫酸镁组治疗成功28例,成功率84.8％;对照组仅4例成功(13.8％),两组有高度显著性差异(P<0.01)。硫酸镁组新生儿窒息率低于对照组(P<0.01),产后出血量及出血率两组无差异(P>0.05)。静脉输入大剂量硫酸镁对母胎无毒副作用。故认为早产应用硫酸镁治疗安全,且效显著,可作为首选药物。
The article retrospectively analyzed the clinical data of 33 cases of premature labor treated with magnesium sulfate from January 1990 to January 1995 and compared with 29 cases of preterm labor using bedside plus sedation in the same period. The results showed that 28 cases were successfully treated with magnesium sulfate group, the success rate was 84.8%. Only 4 cases in the control group were successful (13.8%). There was a highly significant difference between the two groups (P <0.01). The rate of neonatal asphyxia in magnesium sulfate group was lower than that in control group (P <0.01), and there was no difference in postpartum hemorrhage and hemorrhage between the two groups (P> 0.05). Intravenous administration of large doses of magnesium sulfate on the mother’s non-toxic side effects. Therefore, premature delivery of magnesium sulfate treatment, and effective, can be used as the drug of choice.