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[目的]了解上海市宝山区乙型肝炎病毒(HBV)垂直传播的现状,为优生优育的卫生宣教提供依据。[方法]对2010年9月—2011年6月在本院妇产科住院分娩的632例产妇中乙肝表面抗原(HBsAg)阳性或/和乙肝核心抗原(HBeAg)阳性的孕妇及其所产新生儿的脐带血进行HBV血清学标志物检测。[结果]HBV阳性孕妇共236例,占孕妇数的37.34%,其中HBsAg阳性者93例,占39.41%。在对应的236例新生儿脐带血中,HBV阳性56例,阳性率为23.73%,其中男婴30例,占男婴总数的22.90%,女婴26例,占女婴总数的24.76%。新生儿HBsAg阳性8例,占新生儿总数的3.38%。143例剖宫产新生儿的脐带血HBV阳性32例,阳性率为22.38%,93例阴道分娩新生儿的脐带血HBV阳性24例,阳性率为25.80%。[结论]胎盘可以阻止部分HBV进入胎儿体内。新生儿HBV阳性率与分娩方式及新生儿性别无关。
[Objective] To understand the status of hepatitis B virus (HBV) vertical transmission in Baoshan District of Shanghai and provide the basis for health education of prenatal and postnatal care. [Methods] A total of 632 pregnant women with HBsAg positive or / and HBeAg positive pregnant women and their newborn born in our hospital from September 2010 to June 2011 were analyzed retrospectively. Children’s cord blood serum HBV markers. [Results] A total of 236 HBV positive pregnant women, accounting for 37.34% of pregnant women, of which 93 cases HBsAg positive, accounting for 39.41%. In the corresponding cord blood of 236 neonates, 56 were positive for HBV, the positive rate was 23.73%. Among them, 30 were male babies, accounting for 22.90% of the total number of babies and 26 were female babies, accounting for 24.76% of the total. Neonates HBsAg positive in 8 cases, accounting for 3.38% of the total number of newborns. Among 143 cesarean section neonates, 32 cases were positive for cord blood HBV, the positive rate was 22.38%. The positive rate of HBV in 24 cases of neonates with vaginal delivery was 24 cases, the positive rate was 25.80%. [Conclusion] The placenta can prevent some HBV from entering the fetus. Neonatal HBV positive rate and delivery methods and neonatal sex has nothing to do.