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目的:了解糖尿病足坏疽患者的病原菌分布与药敏状况,为临床治疗糖尿病足合并感染患者合理选择抗菌药物提供依据。方法:对2009年4月~2013年6月收治的共计106例糖尿病足坏疽患者分泌物进行病原菌的培养和药敏结果分析。结果:采集106例标本送检,共培养出病原菌103株,同时存在两种或以上病原菌的患者11名,其中培养出两种病原菌者6名,有3种病原菌者5名;共有87例(82.08%)培养出了致病菌,19例(17.92%)未培养出致病菌。包括革兰阳性球菌35株(33.98%),革兰阴性杆菌52株(50.49%),其中厌氧菌13株;真菌16株(15.53%)。结论:糖尿病足感染可以是革兰氏阳性球菌、革兰氏阴性杆菌、厌氧菌和真菌其中的一菌,也可以是混合菌。因此治疗糖尿病足坏疽患者感染理想方法是在综合治疗的同时选择敏感而有效的抗菌素十分重要。
Objective: To understand the pathogen distribution and drug susceptibility in patients with diabetic foot gangrene, and to provide a basis for the rational selection of antimicrobial agents in patients with diabetic foot complicated infection. Methods: From April 2009 to June 2013, a total of 106 patients with diabetic foot gangrene were collected for pathogen culture and drug susceptibility analysis. Results: A total of 106 specimens were collected for detection, 103 strains of pathogens were co-cultivated, 11 of them were also present with two or more pathogens, of which 6 were two kinds of pathogens and 5 were 3 kinds of pathogens. A total of 87 82.08%) cultivated pathogenic bacteria, 19 cases (17.92%) did not cultivate pathogenic bacteria. Including Gram-positive cocci 35 (33.98%), Gram-negative bacilli 52 (50.49%), of which 13 anaerobic bacteria; fungi 16 strains (15.53%). Conclusion: Diabetic foot infection can be Gram-positive cocci, Gram-negative bacilli, anaerobic bacteria and fungi which bacteria, can also be mixed bacteria. Therefore, the treatment of diabetic foot gangrene infection ideal way is the comprehensive treatment of sensitive and effective selection of antibiotics is very important.