Ring-closure Reaction to Novel Quinoline Derivatives and Their Structural Characterization

• 作 者: 吕银祥 蓝碧健 周辉 徐伟 王静梅 黄永明
• 机 构: Department of Materials Science, Fudan University, Shanghai 200433, China ,Department of Materials S
• 出 处: Chinese Journal of Chemistry
• 发表日期: 2004年08期
• 关键词: closure aldehydes benzaldehyde aromatic bonds quinoline intermolecular condensat

In the condensation of arylaldehydes with arylethylidenemalononitriles, it was found that, besides the normal product dienes a, the ring-closure product quinoline derivatives b can be also obtained in 26%—50% yields. The substituent effects were also examined and a possible reaction mechanism was proposed for the formation of b. The X-ray crystal structure of 1b confirms the structure of the ring-closure product.

In the condensation of arylaldehydes with arylethylidenemalononitriles, it was found that, besides the normal product dienes a, the ring-closure product quinoline derivatives b can be also obtained in 26% -50% yields. The substituent effects were also examined and a possible reaction mechanism was proposed for the formation of b. The X-ray crystal structure of 1b confirms the structure of the ring-closure product.