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目的：：探讨品管圈活动在减少静脉药物调配中差错应用的效果。方法：为实现“降低配置差错”，成立品管圈小组。以每周差错发生总数为指标分析现状，以“二八法则”计算出改善目标值。采用头脑风暴法找出产生这一问题的具体原因。采用鱼骨分析法并依据“二八法则”找出主要原因，总结出对策并实施。最后以实施前后无形和有形成果为依据检验实施效果，并提出改进措施。结果：在推行品管圈活动之后，静脉药物配置过程中的差错数由47件/周，下降到22件/周，目标达标率为104.1%，进步率为53.2%。参与人员的主人翁意识、协调能力、团队精神、责任感和信心均得到了提高，提高了分析总结问题能力。结论：品管圈活动对于降低静脉药物配置中心差错有明显提升作用，通过开展该管理手段能够深入发掘和分析静脉药物配置中心内部所出现的问题，通过科学有效的方法制定解决对策，可有效地提升静脉药物配置中心药师、护士服务观念，提高药师在控制配置中的质量管控能力，保证患者用药安全。“,”Objective:To explore the effect of quality control circle ( QQC) on the error control in PIVAS. Methods:QQC group was established in the department of PIVAS to reduce the errors in intravenous admixture practice. The status was analyzed using the total errors per week as the index, and the improvement target value was calculated by the eighty-twenty rule. The concrete causes for the errors were found out by the method of“brain storm”, and the main causes were confirmed using a fishbone diagram and the eighty-twenty rule, and then some countermeasures were summarized and carried out. The application effect of QQC was judged by the intan-gible and tangible outcomes before and after the activity, and some suggestions for the further improvement were provided. Results:Af-ter the implementation of QQC activity, the number of errors was reduced from 47 per week to 22 per week with the rate of target a-chievement of 104. 1% and the progress rate of 53. 2%. Moreover, QQC showed positive influence on the sense of being masters, co-operation ability, team spirit and sense of responsibility and confidence in the whole staff, and the ability of analyzing, summarizing and solving problems was also enhanced. Conclusion: QQC can significantly reduce the errors in the practice of intravenous admix-ture. The management method is valuable to explore and analyze the deep problems encountered in PIVAS in order to make rational and efficient measures. It is also helpful to improving the service conception of pharmacists and nurses, and enhancing the roles of pharma-cists in quality management and control to ensure medication safety.