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目的观察纳米晶体银敷料治疗烧伤患者的临床疗效。方法 56例烧伤患者,随机分为观察组和对照组,每组28例。对照组患者进行常规治疗,观察组患者在常规治疗的基础上予以纳米晶体银敷料配合皮维碘软膏使用。比较两组患者的临床治疗效果、愈合率、创面愈合时间及不良反应发生情况。结果观察组治疗总有效率为85.7%,高于对照组的60.7%,差异具有统计学意义(P<0.05)。观察组患者的创面愈合时间为(12.5±1.2)d,短于对照组的(16.7±0.9)d,差异具有统计学意义(t=14.816,P<0.05)。观察组的创面愈合率为(92.3±1.4)%,高于对照组的(88.6±1.6)%,差异具有统计学意义(t=9.209,P<0.05)。观察组不良反应发生率为3.6%(1/28),对照组为21.4%(6/28),观察组不良反应发生率低于对照组(χ2=4.082,P<0.05)。结论纳米晶体银敷料在烧伤创面的临床治疗上疗效较好,具有疗效好、见效快、不良反应少等优点,值得临床推广。
Objective To observe the clinical effect of nanocrystalline silver dressing on burn patients. Methods 56 cases of burn patients were randomly divided into observation group and control group, 28 cases in each group. The patients in the control group were treated routinely. The patients in the observation group were treated with nanocrystalline silver dressing and piroxicam ointment on the basis of routine treatment. The clinical effects, healing rate, wound healing time and adverse reactions of the two groups were compared. Results The total effective rate of observation group was 85.7%, which was higher than that of control group (60.7%), the difference was statistically significant (P <0.05). The wound healing time in the observation group was (12.5 ± 1.2) d, shorter than that in the control group (16.7 ± 0.9) d, the difference was statistically significant (t = 14.816, P <0.05). The wound healing rate in the observation group was (92.3 ± 1.4)%, which was higher than that in the control group (88.6 ± 1.6)%, the difference was statistically significant (t = 9.209, P <0.05). The incidence of adverse reactions in the observation group was 3.6% (1/28) in the control group and 21.4% (6/28) in the control group. The incidence of adverse reactions in the observation group was lower than that in the control group (χ2 = 4.082, P <0.05). Conclusion The nanocrystalline silver dressing is effective in clinical treatment of burn wounds and has the advantages of good curative effect, quick response and few adverse reactions, which is worthy of clinical promotion.