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为了对全缘叶紫珠的茎和叶进行化学成分研究,采用硅胶、凝胶等柱色谱方法分离和纯化化合物,根据理化性质和波谱方法鉴定化合物结构。从全缘叶紫珠的甲醇提取物中分离得到了15个三萜类化合物,包括1个新化合物:2α,3β,19α,23-tetrahydroxy-olean-12-en-28-oic acid-28-O-β-D-glucopyranosyl-(1→4)-β-D-glucopyranoside(1)和14个已知化合物:oleanolic acid(2)、3-acetyl oleanolic acid(3)、3β-O-acetyl ursolic acid(4)、2α-hydroxy-ursolic acid(5)、2α,3β,19α,23-tetrahydroxy-urs-12-en-28-oic acid(6)、α-amyrin-3-O-β-D-glucopyranoside(7)、pomolic acid(8)、betulinic acid(9)、ursolic acid(10)、2α,3β,19α,23-tetrahydroxy-olean-12-en-28-oic acid(11)、2α-hydroxy-oleanolic acid(12)、hederagenin(13)、2α,19α-dihydroxy-ursolic acid(14)和pruvuloside A(15)。所有化合物均为首次从全缘叶紫珠中分离得到,其中化合物3、4和15为首次从紫珠属中分离得到。
In order to study the chemical constituents of the stem and leaf of the whole leaf, the compounds were isolated and purified by column chromatography on silica gel and gel, and the structures of compounds were identified by their physico-chemical properties and spectroscopic methods. Fifteen triterpenoids were isolated from the methanolic extracts of the leaves of Periplocaceae and included one new compound: 2α, 3β, 19α, 23-tetrahydroxy-olean-12-en-28-oic acid- β-D-glucopyranosyl- (1 → 4) -β-D-glucopyranoside (1) and 14 known compounds: oleanolic acid (2), 3-acetyl oleanolic acid 4, 2α-hydroxy-ursolic acid (5), 2α, 3β, 19α, 23-tetrahydroxy-urs-12- en- 28-oic acid (6), α-amyrin-3-O-β-D-glucopyranoside (7) pomolic acid (8) betulinic acid (9) ursolic acid (10) 2α 3β 19α 23-tetrahydroxy-olean- oleanolic acid (12), hederagenin (13), 2α, 19α-dihydroxy-ursolic acid (14) and pruvuloside A (15). All the compounds were isolated from the whole leaf Vitex for the first time, of which compounds 3, 4 and 15 were isolated from the genus Ureaplasma for the first time.