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目的探讨手术联合辅助治疗应用于局部复发性直肠癌的治疗效果。方法对1993年8月至2002年2月间收治的107例局部复发再治疗的患者不同治疗方法的疗效进行回顾性分析。结果手术联合辅助治疗(A组)32例,单纯手术(B组)37例,辅助治疗(C组)38例,3组中位年龄分别为:(49.3±20.7)、(44.4±25.4)、(52.9±29.1)岁。A、B、C组中位生存期分别为27.8、14.6、13.7个月。A组5年生存率显著优于B组和C组(P<0.05)。结论对于复发性直肠癌行包括积极的手术在内的综合治疗可以给患者带来长期生存的机会。
Objective To investigate the therapeutic effect of surgical combined adjuvant therapy on locally recurrent rectal cancer. Methods A retrospective analysis was performed on the efficacy of different treatment methods in 107 patients with locally recurred and re-treated patients admitted between August 1993 and February 2002. Results There were 32 cases in operation combined with adjuvant therapy (group A), 37 cases in simple operation (group B) and 38 cases in adjuvant therapy (group C). The median age of three groups were (49.3 ± 20.7) and (44.4 ± 25.4) (52.9 ± 29.1) years old. The median survival time in groups A, B and C was 27.8, 14.6 and 13.7 months respectively. The 5-year survival rate of group A was significantly better than that of group B and C (P <0.05). Conclusion Comprehensive treatment, including aggressive surgery, for recurrent rectal cancer can give patients long-term survival opportunities.