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目的探讨儿童格林－巴利综合征（ＧＢＳ）植物神经功能紊乱的发病情况，及发病机理，指导临床用药。方法将１０６例ＧＢＳ患儿按有无植物神经功能紊乱分为两组，统计各种植物神经功能紊乱症状、体征所占比例，两组的病程与转归情况。结果儿童ＧＢＳ伴发植物神经功能紊乱以窦性心动过速最多见（２７．３％），其它尚有血压异常、瞳孔改变、尿便障碍等，多发生于病情进展期。伴发植物神经功能紊乱组其死亡率、气管切开率、使用呼吸机时间等均显著高于无植物神经功能紊乱组（Ｐ＜０．０１）。结论植物神经功能紊乱是儿童ＧＢＳ常见合并症，且是主要的危险因素，以心血管系统功能紊乱最多见。正确认识这些症状，以便合理治疗。
Objective To investigate the incidence of autonomic dysfunction in children with Guillain-Barre Syndrome (GBS) and its pathogenesis, and to guide the clinical application. Methods 106 cases of GBS children with or without autonomic dysfunction were divided into two groups, statistics of various autonomic dysfunction symptoms, the proportion of signs, duration and outcome of the two groups. Results The majority of children with GBS complicated with autonomic dysfunction were sinus tachycardia (27.3%), others had abnormal blood pressure, pupil changes and urinary stool disorders, which occurred in the progression of the disease. The mortality, tracheotomy rate, ventilator time and other parameters in patients with autonomic dysfunction were significantly higher than those without autonomic dysfunction (P <0.01). Conclusions Autonomic dysfunction is a common comorbidity of GBS in children and is a major risk factor with the most common cardiovascular disorders. Correct understanding of these symptoms, so that reasonable treatment.