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目的探讨超声引导下冷循环微波刀治疗肝癌的临床效果及安全性。方法选择2006-04-2010-06在邯郸市中心医院接受冷循环微波刀治疗的肝癌患者113例,观察手术前后AFP浓度及肝功能变化,用彩超及CT比较肿瘤大小及血供变化。结果术前血清AFP为(523±32.5)μg/L,手术1周后明显降为(248±24.1)μg/L;肝功能在术后1周出现轻度变化,3周后逐渐改善。术后复查彩超及CT,肿瘤血供减少或消失,增强CT显示强化灶减弱或消失。全组无严重并发症及手术死亡病例。结论冷循环微波刀具有安全有效、创伤小、操作简便等优点,是对手术治疗肝癌方法的重要补充。
Objective To investigate the clinical effect and safety of ultrasound guided cold cycle microwave knife in the treatment of liver cancer. Methods A total of 113 hepatocellular carcinoma (HCC) patients treated with microwave-assisted microwave knife in Handan Central Hospital from April 2006 to June 2010 were enrolled. The changes of AFP and liver function were observed before and after operation. The size of the tumor and blood supply were compared by color Doppler sonography and CT. Results Preoperative serum AFP was (523 ± 32.5) μg / L and decreased significantly to (248 ± 24.1) μg / L after 1 week of operation. Liver function changed slightly 1 week after operation and gradually improved after 3 weeks. Postoperative ultrasound and CT scan, tumor blood supply decreased or disappeared, enhanced CT showed focal lessened or disappeared. The whole group without serious complications and surgical deaths. Conclusion Cold cycle microwave knife has the advantages of safe and effective, less trauma and simple operation, which is an important supplement to the surgical treatment of liver cancer.