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目的探讨低密度脂蛋白胆固醇(LDL-C)正常的不稳定型心绞痛患者介入术后超敏C反应蛋白(hs-CRP)与预后的关系。方法选择80例LDL-C正常水平的不稳定型心绞痛患者,测定其经皮冠状动脉介入术前血清hs-CRP水平,介入术后随访9个月,观察主要不良心血管事件的发生率。结果高hs-CRP组主要不良心血管事件发生率显著高于正常组(P<0.05)。结论 hs-CRP可预测接受PCI治疗的LDL-C正常的不稳定型心绞痛患者心血管事件的发生,对判断预后具有重要临床意义。
Objective To investigate the relationship between hs-CRP and prognosis after interventional therapy in patients with unstable angina with low-density lipoprotein cholesterol (LDL-C). Methods Eighty patients with unstable angina pectoris at the normal level of LDL-C were enrolled in this study. Serum hs-CRP levels were measured before percutaneous coronary intervention. The incidence of major adverse cardiovascular events was observed after 9 months of follow-up. Results The incidence of major adverse cardiovascular events in high hs-CRP group was significantly higher than that in normal group (P <0.05). Conclusions hs-CRP can predict the occurrence of cardiovascular events in patients with unstable angina pectoris of LDL-C treated with PCI, which has important clinical significance in judging the prognosis.