论文部分内容阅读
近年来,越来越多的抗炎镇痛新药已经用于风湿病的治疗,这些药物临床作用的基础在于抑制前列腺素的合成,然而它们在不同的疾病中有不同的作用。由于它们精细的作用方式不尽相同,其药理作用和毒性也差异很大,特别是不同病人对不同的非甾体抗炎药(NSAID)有完全不同的反应。因此,试制多种药物以适应治疗的个体化,对各种病人寻求最有效的治疗方案是很有价值的,同时必须记住这些药物
In recent years, more and more anti-inflammatory and analgesic new drugs have been used for the treatment of rheumatism. The basis of the clinical effect of these drugs is to inhibit prostaglandin synthesis, however, they have different effects in different diseases. Pharmacological effects and toxicity vary greatly depending on their precise mode of action. In particular, different patients have completely different responses to different NSAIDs. Therefore, it is valuable to try out a variety of medicines to adapt to the individualization of treatment and to find the most effective treatment for a variety of patients, keeping in mind that these drugs