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目的了解金华市健康人群流行性腮腺炎病毒抗体水平。方法采集健康人群血清标本1 175份,采用酶联免疫吸附试验定量检测腮腺炎Ig G抗体。结果人群血清中腮腺炎抗体阳性率为80.00%,几何平均浓度(geometric mean concentration,GMC)为112.49 IU/ml。不同性别和不同户籍人群的抗体阳性率和GMC差异无统计学意义(P>0.05);13个年龄组抗体阳性率及GMC差异有统计学意义(χ2=296.765,P<0.001),GMC最低的为8月龄~组(6.13 IU/ml),最高的为30岁~组(275.63 IU/ml)。结论预测金华市近期不会发生流行性腮腺炎暴发流行。建议继续做好流行性腮腺炎疫情监测工作,及时开展麻风腮疫苗加强免疫,减少病毒感染的风险。
Objective To understand the level of mumps virus in healthy population in Jinhua City. Methods A total of 1 175 serum samples from healthy subjects were collected and the Ig G antibody of mumps was quantitatively detected by enzyme-linked immunosorbent assay (ELISA). Results The positive rate of mumps antibody in the population was 80.00%, and the geometric mean concentration (GMC) was 112.49 IU / ml. There was no significant difference in antibody positive rate and GMC between different sexes and different hukou populations (P> 0.05). The antibody positive rate and GMC in 13 age groups were statistically significant (χ2 = 296.765, P <0.001) 8 months old ~ group (6.13 IU / ml), the highest is 30 years old ~ group (275.63 IU / ml). Conclusions The epidemic of mumps will not occur in Jinhua City in the near future. It is recommended to continue monitoring the epidemic situation of mumps and promptly carry out the immunization with the mumps vaccine to reduce the risk of virus infection.