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目的:观察经皮二尖瓣球囊扩张术(PBMV)治疗风湿性二尖瓣狭窄的中远期疗效。方法:采用Inoue单球囊对150例风湿性二尖瓣狭窄患者行PBMV治疗,并进行了长期随访,随访时间12～96(46±22)月。结果:二尖瓣瓣口面积由0.98±0.16cm~2增至1.86±0.54cm~2,二尖瓣平均跨瓣压差由19.6±7.2mmHg降至10.3±5.6mmHg,10例出现明显再狭窄,其中6例再次行PB-MV术,4例行瓣膜置换术。结论:PBMV治疗风湿性二尖瓣狭窄的中远期效果良好,瓣下病变的严重程度将影响中远期疗效。
Objective: To observe the long-term therapeutic effect of percutaneous balloon mitral valvuloplasty (PBMV) on rheumatic mitral stenosis. Methods: One hundred and fifty patients with rheumatic mitral stenosis were treated with PBMV by Inoue single balloon and were followed up for a long period of 12 to 96 (46 ± 22) months. Results: The mitral valve orifice area increased from 0.98 ± 0.16cm 2 to 1.86 ± 0.54cm 2, mean mitral valve pressure transmural drop from 19.6 ± 7.2mmHg to 10.3 ± 5.6mmHg, and 10 cases showed obvious restenosis , Of which 6 cases again PB-MV surgery, 4 cases of valve replacement surgery. Conclusion: The long-term effect of PBMV in the treatment of rheumatic mitral stenosis is good. The severity of the subvalvular lesion will affect the long-term therapeutic effect.