论文部分内容阅读
目的:探讨血液病儿童在大剂量化疗或造血干细胞移植前拔牙的安全性指标。方法:对65名住院血液病患儿在化疗或造血干细胞移植前实施病灶牙拔除,拔牙前检查血象,拔牙后观察止血时间,控制感染及创口愈合情况等。结果:65例患儿的102颗患牙顺利拔除。3例出现创口延期愈合,均未出现严重并发症和血液病恶化状况,并在拔牙后1～2周内顺利开始化疗或干细胞移植。结论:当血小板计数在60～300×109/L,白细胞计数在3.0～10.0×109/L时,拔牙是安全的。血小板计数在低于60×109/L时,最好提前输入新鲜血小板。白细胞计数1.5～3.0×109/L时,控制感染十分重要。
Objective: To explore the safety of children with hematological disorders before tooth extraction with high-dose chemotherapy or hematopoietic stem cell transplantation. Methods: Totally 65 children with in-hospital hematological diseases were treated with dental extraction before chemotherapy or hematopoietic stem cell transplantation, blood tests before tooth extraction, bleeding time after tooth extraction, infection control and wound healing. Results: A total of 102 teeth in 65 children were successfully removed. No wounds developed in 3 cases, and no serious complication and hematological deterioration were observed. Chemotherapy or stem cell transplantation was successfully started within 1 to 2 weeks after tooth extraction. Conclusion: Tooth extraction is safe when the platelet count is 60-300 × 109 / L and the white blood cell count is 3.0-10.0 × 109 / L. Platelet count below 60 × 109 / L, it is best to enter the fresh platelets in advance. WBC count 1.5 ~ 3.0 × 109 / L, the control of infection is very important.