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男性,17岁。半月前劳动后发现左下肢踝部肿胀,皮肤青紫,继而双下肢出现散在性大块淤斑,稍有压痛,不痒。次日起咳嗽、咯血痰,并有尿频、尿急、腰痛,排血尿四次,无明显畏寒、发热。三日后症状加重,行走困难。当地医院疑为“过敏性紫癜”,经用青霉素、链霉素、强的松、扑尔敏、氢化考的松等治疗,并输血500ml,疗效不显著。过去体健,1972年因游泳碰伤左小腿,虽有大块皮肤损伤但用一般止血处理后出血即停止。发病前两天,手指破损后出血不止。父母及一妹均健康,父系和母系亲属中均无
Male, 17 years old. Half a month ago found the left lower extremity ankle swelling, skin bruising, and then appear in both lower extremities scattered bulk ecchymosis, a little tenderness, itch. The next day cough, hemoptysis sputum, and frequent urination, urgency, low back pain, hematuria four times, no significant chills, fever. After three days the symptoms worsened, walking difficulties. Local hospital suspected “allergic purpura”, by penicillin, streptomycin, prednisone, chlorpheniramine, hydrocortisone and other treatment, and blood transfusion 500ml, curative effect is not significant. In the past, physical fitness, left leg injury in 1972 due to swimming bumps, although there are large skin lesions but bleeding with the general stop bleeding after treatment. Two days before the onset of bleeding after the finger is broken. Parents and a girl are healthy, no paternal and matrilineal relatives