论文部分内容阅读
目的研究内蒙古地区蒙族和汉族人群CYP1A1基因MspⅠ位点的多态性。方法应用聚合酶链反应限制性片段长度多态技术对无血缘关系的80名蒙族和120名汉族个体的基因型进行分析。结果内蒙古地区蒙族和汉族人群CYP1A1基因wt/wt、wt/vt和vt/vt3种基因型的频率分布分别是:蒙族35.0%、48.7%、16.3%和汉族33.3%、52.5%、14.2%。两者之间经χ2检验差异无统计学意义(P>0.05)。结论内蒙古地区蒙族和汉族人群CYP1A1基因MspⅠ的基因型频率分布无明显差异。
Objective To study the polymorphism of CYP1A1 gene MspⅠ in Mongolian and Han nationality in Inner Mongolia. Methods Polymerase chain reaction restriction fragment length polymorphism (PCR-RFLP) was used to analyze the genotypes of 80 Mongolian and 120 Han unrelated individuals. Results The frequencies of wt / wt, wt / vt and vt / vt genotypes of CYP1A1 gene in Mongolian and Han nationalities in Inner Mongolia were 35.0%, 48.7%, 16.3% and 33.3%, 52.5% and 14.2%, respectively. No significant difference between the two by χ2 test (P> 0.05). Conclusion There was no significant difference in the genotype frequency of CYP1A1 gene between Mongolian and Han nationality in Inner Mongolia.