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目的:比较黄芪加味汤与西沙比利片用于治疗老年慢性性功能性便秘患者的临床疗效。方法:选取2012年10月—2014年10月间收治确诊的慢性功能性便秘老年患者120例,将其随机分为对照组和观察组(各60例);对照组患者予口服西沙比利片治疗,观察组患者予服用黄芪加味汤,比较两组患者的临床疗效、复发率及药物不良反应的发生情况。结果:治疗4周后观察近期疗效,观察组患者治疗的总有效率为93.33%显著高于对照组为75.00%(P<0.05);停药3月后观察复发率,观察组患者复发率低于对照组(P<0.05);治疗后两组患者临床证候积分值均明显下降,且观察组临床证候积分值明显低于对照组(P<0.05);治疗期间两组患者均未出现明显药物不良反应。结论:黄芪加味汤用于治疗老年慢性功能便秘患者的疗效优于西沙比利片的治疗,且复发率低。
Objective: To compare the clinical curative effect of astragalus flavored soup and cisapride tablets in the treatment of elderly patients with chronic functional constipation. Methods: A total of 120 senile patients with chronic functional constipation admitted from October 2012 to October 2014 were selected and randomly divided into control group and observation group (60 cases each). Patients in the control group were given cisapride tablets orally The patients in observation and treatment groups were given astragalus plus soup, and the clinical efficacy, relapse rate and adverse drug reactions were compared between the two groups. Results: After 4 weeks of treatment, the short-term curative effect was observed. The total effective rate of the observation group was 93.33%, which was significantly higher than that of the control group (75.00%) (P <0.05). The relapse rate was observed after 3 months and the recurrence rate In the control group (P <0.05). After treatment, the scores of clinical syndromes in both groups were significantly decreased, and the clinical syndrome scores in the observation group were significantly lower than those in the control group (P <0.05) Obvious adverse drug reactions. Conclusion: Astragalus flavored soup is superior to cisapride tablets in the treatment of elderly patients with chronic functional constipation, and the recurrence rate is low.