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目的探讨腹腔镜肝切除(LH)的临床应用价值及其对机体免疫功能的影响。方法选择符合纳入标准的45例行肝切除患者随机分入LH组和开腹肝切除(OH)组。比较两组患者的平均切口长度、手术时间、术中出血量、术后进食时间、术后止痛药的用量、术后住院天数、有无并发症、围手术期体温变化及血象的变化。结果 LH组在切口长度、出血量、进食时间、术后止痛药用量、术后住院时间及围手术期体温均明显少于OH组(均P<0.05),两组手术时间相仿,均无严重并发症(P<0.05)。结论在病例选择适当时,腹腔镜肝切除术安全、可行、临床效果确切,对机体免疫影响小,近期疗效明显优于开腹手术。
Objective To investigate the clinical value of laparoscopic liver resection (LH) and its effect on immune function. Methods Forty-five patients undergoing hepatectomy who met the inclusion criteria were randomly divided into LH group and open hepatectomy group. The average incision length, operation time, intraoperative blood loss, postoperative eating time, postoperative analgesic dosage, postoperative hospital days, complications and complications, perioperative temperature changes and blood changes were compared between the two groups. Results The length of incision, blood loss, feeding time, analgesic dosage, postoperative hospital stay and perioperative body temperature in LH group were significantly less than those in OH group (all P <0.05). There was no significant difference between the two groups Serious complication (P <0.05). Conclusions Laparoscopic hepatectomy is safe, feasible and definite in clinical practice. It has little effect on the immune system and has better curative effect in the near future than laparotomy.