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目前,国内水族馆的规模逐渐扩大,但由于饲养条件和医疗水平有限,从而使动物易患各种疾病,其中消化道疾病发病率高达50%,主要致病因素有幽门螺杆菌(HP)、大肠杆菌、异尖线虫感染,紧张性应激,负强化的训练方式及异物损伤等。幽门螺杆菌(HP)是一种弯曲状的革兰氏阴性菌,该菌发现以来,其感染作为慢性胃炎、消化性溃疡和胃癌发生的主要病因已得到医学界的认可。流行病学调查显示饮用水与HP感染关系密切,支持HP经水传播的观点[1]。
At present, the scale of domestic aquariums is gradually expanding. However, due to the limited breeding conditions and medical conditions, animals are susceptible to various diseases, of which the prevalence of gastrointestinal diseases is as high as 50%. The main causative agents are Helicobacter pylori (HP) Escherichia coli, Anisakis infection, stress, negative reinforcement of training methods and foreign body damage. Helicobacter pylori (HP) is a curved, Gram-negative bacterium whose infection has been recognized by the medical profession as a major cause of chronic gastritis, peptic ulcer and gastric cancer since its discovery. Epidemiological studies have shown that drinking water and HP infection are closely related to support the HP by water transmission point of view [1].