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选取2012年6月~2013年12月我科收治的16例AML患者,分为对照组7例和观察组9例。观察组采用用地西他滨联合半量CAG治疗,对照组单用地西他滨治疗。比较两组疗效和不良反应。结果 2个疗程后,两组ORR比较差异有显著意义(P<0.05),血液学不良反应均达到Ⅲ~Ⅳ度,差异无统计学意义(P>0.05)。地西他滨联合半量CAG治疗方案对AML有一定疗效,值得深入探索。
Sixteen patients with AML admitted from June 2012 to December 2013 in our department were divided into control group (n = 7) and observation group (n = 9). The observation group was treated with decitabine combined with CAG and the control group was treated with decitabine alone. The efficacy and adverse reactions of the two groups were compared. Results After two courses of treatment, there was significant difference in ORR between the two groups (P <0.05). The adverse reaction of hematology reached grade Ⅲ ~ Ⅳ, with no significant difference (P> 0.05). Decitabine combined with semi-dose CAG treatment of AML has a certain effect, it is worth exploring in depth.