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目的临床观察胺碘酮联合美托洛尔治疗心房纤颤(简称房颤)的疗效及副作用。方法 60例房颤的老年患者,均采用口服胺碘酮0.2g/次,3次/d,应用一周,第二周改为0.2g/次,2次/d,第三周改为1次/d维持;美托洛尔6.25mg,2次/d,开始加大剂量至25mg,2次/d,口服治疗。随访一年。结果在二周内复律44例,成功率达73.3%。随访一年,显效者40例,占66.7%,有效6例,总有效率76.7%。无严重心律失常发生,未诱发加重心功能不全。结论胺碘酮联合美托洛尔治疗房颤疗效明显,毒副作用少。
Objective To observe the efficacy and side effects of amiodarone combined with metoprolol in the treatment of atrial fibrillation (AF). Methods 60 elderly patients with atrial fibrillation were treated with oral amiodarone 0.2g / time for 3 times / d for one week, then 0.2g / time for the second week, twice / d for the third week and once for the third week / d to maintain; metoprolol 6.25mg, 2 times / d, began to increase the dose to 25mg, 2 times / d, oral treatment. Followed by one year. The results of cardioversion in 44 cases within two weeks, the success rate of 73.3%. One year follow-up, 40 cases were markedly effective, accounting for 66.7%, effective in 6 cases, the total effective rate was 76.7%. No serious arrhythmia occurred, did not induce increased cardiac dysfunction. Conclusions Amiodarone combined with metoprolol has obvious curative effect on atrial fibrillation with few side effects.