Effects of transient global ischemia on the neurons in the marginal division of the rat striatum

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Transient global ischemia frequently occurs following cardiac arrest and causes ischemic brain injury and vascular dementia.It wassuppised that the injury of neurons in the hippocampus formation sponsors the cognitive defictis.But recently this view has been challenged bya number of experiments.A memory process,objective recognition,found to be largely intact following selective hippocampal formation lesionsboth in monkeys and rats.Some of the extra-hippocampal damages are involved in the process of learning and memory.The marginal division(MrD)is a new subdivision in the striatum firstly discovered by Si Yun Shu in 1988.It is consisted of a band of fusiform neurons at the caudalmargin of the striatum.Depression of learning and memory occurred following injury of MrD.Global cerebral ischemia models were conducted by4-vessel occlusion.Ischemia induced hydrocephalus in hippocapus,cortex and striatum almost at same level.MrD was the injured by ischemia.Y-maze test demonstrated distinct and stable impairmen Transient global 1 2 3 4 5 4 5 6 5 6 5 6 6 6 5 6 6 6 6 6 10 15 30 30 30 30 30 30 30 30 30 30 30 30 30 30 30 30 30 30 30 30 30 30 30 30 30 30 30 30 30 30 30 30 30 30 30 Insuh. recognition, found to be much intact following selective hippocampal formation lesions in monkeys and rats. Home of the extra-hippocampal damages are involved in the process of learning and memory.The marginal division (MrD) is a new subdivision in the striatum first discovered by Si Yun Shu in 1988. It is consisted of a band of fusiform neurons at the caudal margin of the striatum. Depression of learning and memory occurred following injury of MrD. Global cerebral ischemia models were conducted by 4-vessel occlusion. Ischemia induced hydrocephalus in hippocapus, cortex and striatum almost at same level. Male was the injured by ischemia. Y-maze test demonstrated distinct an d stable impairmen
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