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目的探讨定量组织速度成像(QTVI)评价不同PTH水平维持性血液透析患者的心肌功能。方法应用QTVI技术对20例健康人及40例尿毒症患者分成PTH<正常值上限3倍,PTH>正常值上限3倍两组,每组各20例,分别进行不同节段心肌运动速度测量,即收缩期S波,舒张期E、A波,同时测定其相应的时间-速度积分(S-TV I)位移的大小。结果 QTVI显示不同PTH水平维持性血液透析患者的心肌功能较正常人减低。两组患者E波、S及S-TV I均低于正常组的相应心肌节段,差异有显著意义P<0.05。PTH>正常值上限3倍的尿毒症患者心肌功能的减退程度更为严重。结论 QTVI技术能够早期、客观、准确的发现患者心肌细胞损伤的变化,为PTH对心肌的损害提供了客观、定量的理论依据。
Objective To investigate the quantitative myocardial velocity imaging (QTVI) for evaluating myocardial function in maintenance hemodialysis patients with different PTH levels. Methods Twenty healthy people and 40 uremic patients were divided into three groups: PTH <3 times of upper limit of normal value and PTH> 3 times upper limit of normal value by QTVI technique. Twenty patients in each group were respectively measured myocardial velocity, That is, systolic S wave, diastolic E, A wave, and the corresponding time-velocity integral (S-TV I) displacement size. Results QTVI showed that myocardial function in maintenance hemodialysis patients with different levels of PTH was lower than that in normal subjects. E wave, S and S-TV I in both groups were lower than the corresponding myocardial segments in normal group, the difference was significant (P <0.05). Uremic patients with PTH> 3 times the upper limit of normal have a greater degree of diminished myocardial function. Conclusion QTVI technique can detect the change of myocardial cell injury early, objectively and accurately, and provide an objective and quantitative theoretical basis for the damage of myocardium by PTH.