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Up to now,no antiviral therapeutic regimens with exact efficacy are recommended to be used in children with coronavirus disease 2019 (COVID-19).Interim Guidance for Diagnosis and Treatment (the sixth edition) of COVID-19 [1] only provided potential antiviral treatments in adults.According to the current guidelines for management in adults and children and available resources in antiviral drugs,we herein discussed the pharmaceutical care of the five antiviral treatments (IFN-α,lopinavir/ritonavir,ribavirin,chloroquine diphosphate and arbidol) in children with COVID-19 (Table 1).