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目的:分析宫颈疾病患者的人乳头瘤病毒(HPV)感染及相关情况,为宫颈疾病的防治提供线索和依据。方法:收集2009年7月~2010年5月210例宫颈疾病患者的宫颈外口和宫颈脱落细胞及分泌物进行HPV-PCR的检测。结果:HPV感染的阳性率为30.00%,HPV阳性患者的平均年龄为(24.16±8.18)岁,HPV阴性患者平均年龄为(36.94±9.95)岁;HPV的感染与患者的受教育水平,饮酒吸烟及性伴侣多有统计学相关性,HPV阳性患者中饮酒患者占55.56%,吸烟的患者占38.10%;并且运用单危险因素分析发现,月收入、婚姻状况、吸烟状况及性伴侣个数几个因素与HPV感染之间具有相关性。结论:HPV的感染可能与性伴侣个数,吸烟饮酒等多种因素相关;HPV-DNA检测在宫颈病变的检查中具有重要意义。
Objective: To analyze the human papillomavirus (HPV) infection in patients with cervical diseases and related conditions, provide clues and basis for the prevention and treatment of cervical diseases. Methods: HPV-PCR was carried out in 210 cases of cervical diseases from July 2009 to May 2010 with cervical exocervical and cervical exfoliated cells and secretions. Results: The positive rate of HPV infection was 30.00%, the average age of HPV positive patients was (24.16 ± 8.18) years old, and the average age of HPV negative patients was (36.94 ± 9.95) years old. HPV infection and patient’s education level, drinking and smoking And sexual partners were statistically significant, HPV positive patients accounted for 55.56% of drinking alcohol, smoking accounted for 38.10%; and the use of single-risk factor analysis found that monthly income, marital status, smoking status and the number of sexual partners several There is a correlation between factors and HPV infection. Conclusion: HPV infection may be related to the number of sexual partners, smoking and drinking and other factors; HPV-DNA testing in the examination of cervical lesions is of great significance.