论文部分内容阅读
目的:对3例RhD阴性产妇所育的RhD阳性新生儿因D抗原遮蔽造成假阴性现象,进一步进行血型血清学检测及分析。方法:采用血型血清学方法检测新生儿及其母亲、父亲血型抗原、抗体。结果:新生儿血型分别为O,CcDEe、B,CCDEe、A,CcDEe;其母亲分别为O,ccdee、B,ccdee、AB,ccdee;其父亲分别为:O,CcDEe、O,CCDEe、A,CcDEe;新生儿直接抗球蛋白试验分别为:3+、3+、3+。对新生儿进行RhD血型检测时,试管法观察结果未见凝集,易误判为RhD阴性。结论:通过血型血清学检测该3例患儿RhD抗原为阳性,并由Rh系统IgG抗D引起的新生儿溶血病,为新生儿能得到及时治疗提供实验室依据。
OBJECTIVE: To detect false negative results of RhD-positive neonates from 3 RhD-negative mothers due to D antigen occlusion, and to further analyze blood group serology. Methods: Blood type serological methods were used to detect neonatal and their mothers, fathers blood group antigens and antibodies. Results: The newborn blood type were O, CcDEe, B, CCDEe, A, CcDEe. The mothers were O, Cdede, B, Cdee, AB, CcDEe; neonatal direct antiglobulin test were: 3 +, 3 +, 3 +. RhD blood group tests on neonates, the test tube test results no agglutination, easily misjudged RhD negative. Conclusions: RhH antigen was positive by blood group serology and neonatal hemolytic disease caused by IgG anti-D by Rh system, which provided a laboratory basis for timely treatment of neonates.