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目的探讨自主神经功能检测对2型糖尿病患者早期自主神经病变的诊断价值。方法采用病例对照研究,无神经病变表现的2型糖尿病患者34例,正常对照组30例,予皮肤交感反应和心率变异性分析进行自主神经功能检测。结果糖尿病患者的皮肤交感反应和心率变异性与对照组比较差异均有统计学意义(P<0.01)。结论糖尿病自主神经功能状态和检测方法有皮肤交感反应(sympathetic skin response,SSR)和心率变异性(Heart Rate Vatiability),可以作为早期糖尿病患者自主神经功能检测的常规筛选方法。
Objective To investigate the diagnostic value of autonomic nerve function test in patients with type 2 diabetes early autonomic neuropathy. Methods A case-control study of 34 patients with type 2 diabetes mellitus without neuropathy, 30 patients with normal controls was performed. Autonomic nerve function tests were performed on skin sympathetic and heart rate variability. Results The skin sympathetic responses and heart rate variability in diabetic patients were significantly different from those in the control group (P <0.01). Conclusions There are skin sympathetic skin response (SSR) and heart rate variability (HRV) in functional state of diabetic autonomic nerve and its detection methods. It can be used as a routine screening method for autonomic nerve function in patients with early diabetic.