论文部分内容阅读
采用健康小型猪结扎冠状动脉左前降支造成心肌缺血模型,以检测平均动脉压(MAP)、左室收缩峰压(LVSP)、左室舒张终末压(LVEDP)、心率(HR)等指标观察灌服黄芪生脉颗粒剂后对小型猪实验性心肌缺血的影响。并采用TTC染色心肌片,求得梗塞心肌占心室重量的百分比。结果表明,该制剂可明显减轻心肌缺血的程度和范围,减少缺血性心律失常的发生,增加心肌细胞的电生理稳定性
The left anterior descending coronary artery was ligated with healthy miniature pig to establish the model of myocardial ischemia in order to detect the indexes of MAP, LVSP, LVEDP and HR To observe the effect of gavage Huangqi Shengmai Granule on experimental myocardial ischemia in miniature pigs. TTC staining was used to determine the percentage of infarcted myocardium in the ventricular weight. The results show that the preparation can significantly reduce the extent and extent of myocardial ischemia, reduce the incidence of ischemic arrhythmia and increase the electrophysiological stability of myocardial cells