新型脑脊液检测项目在细菌性脑膜炎诊断中的应用

• 作 者: 陈文骞 杨长仪
• 机 构: 福建医科大学教学医院福建省妇幼保健院新生儿科,
• 出 处: 中国新生儿科杂志
• 发表日期: 2015年05期
• 关键词: @@

新生儿细菌性脑膜炎是导致新生儿死亡和严重神经系统后遗症的重要感染性疾病。在发展中国家新生儿细菌性脑膜炎的病死率达40%~58%,远高于发达国家的10%~([1])。细菌性脑膜炎的诊断包括临床诊断及病原学诊断。凡具有感染和细菌性脑膜炎的临床表现,脑脊液常规、生化结果符合细菌性脑膜炎诊断标准者,可临床诊断为细菌性脑膜炎~([2])。但由于新生儿细菌性脑膜炎早期症状不典型,无特异性体征,且传统的脑脊液常规和生化检验结果在

Neonatal bacterial meningitis is an important infectious disease that causes neonatal death and severe neurological sequelae. In developing countries, the mortality rate of bacterial meningitis in newborns is 40% -58%, much higher than that in developed countries (~ 10%). Bacterial meningitis diagnosis includes clinical diagnosis and etiological diagnosis. Where the clinical manifestations of infection and bacterial meningitis, cerebrospinal fluid routine, biochemical results meet the diagnostic criteria of bacterial meningitis, clinically diagnosed as bacterial meningitis ~ ([2]). However, due to neonatal bacterial meningitis atypical early symptoms, no specific signs, and conventional cerebrospinal fluid routine and biochemical test results in