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通过受体的放射配基结合分析,对28例不同程度的先天性尿道下裂患儿外生殖器皮肤细胞的雄激素受体进行了测定,实验显示尿道下裂患儿外生殖器皮肤细胞内雄激素受体量减少,表明雄激素受体异常是先天性尿道下裂的原因之一。
Through the receptor radioligand binding analysis of 28 cases of congenital hypospadias in children with genital skin cells androgen receptor was measured in children with hypospadias genital skin cells androgen testosterone Receptor decreased, indicating that androgen receptor abnormalities is one of the causes of congenital hypospadias.