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为分析甲状腺功能状态在β地贫生长落后患儿中的变化，以探讨甲状腺功能在患儿生长的价值。我们对27例β地贫患儿（重型21例，中间型6例）进行了身高（H）、体重（W）、血红蛋白（Hb）、血清铁蛋白（SF）、三碘甲腺原氨酸（Ts）和甲状腺素（L4）的测定。结果患儿的H、W、Hb均低于正常儿（P＜0．05）；SF高于正常儿（P＜0．05）；Ts、T4在5岁以下组（20例）为正常（P＞0．05），在5岁以上组（7例）低于正常（P＜0．05）。我们认为β地贫患儿的生长落后与长期贫血有关，“甲低”为亚临床型，甲状腺激素水平的低下不仅是生长落后的加重因素。铁的长期沉积比单次检测更有意义。
In order to analyze the changes of thyroid function status in children with β-thalassemia growth and retard the value of thyroid function in children’s growth. In 27 cases of β-thalassemia (21 cases of heavy type and 6 cases of intermediate type), we measured the changes of height, weight, hemoglobin, serum ferritin, triiodothyronine (Ts) and thyroxine (L4). Results H, W and Hb in children were lower than those in normal children (P <0.05); SF was higher than normal children (P <0.05); Ts and T4 were normal in children under 5 years (20 cases) P> 0.05), and were lower than normal in 5 years old group (P <0.05). We believe that the poor growth of children with β-thalassemia and long-term anemia related to “hypothyroidism” as a subclinical type, low thyroid hormone levels not only aggravate the growth of backward factors. Long-term deposition of iron is more meaningful than a single test.