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2型糖尿病患者胰岛功能进行性减退,需要严格控制血糖水平。长期维持理想血糖水平被证明可以降低1型和2型糖尿病患者微血管和大血管并发症发病风险。临床试验表明,噻唑烷二酮类药物(TZDs)单一用药或与二甲双胍和磺脲类药物联用可长期维持理想血糖水平。吡格列酮可降低2型糖尿病患者长期心血管并发症发病率和死亡率。
Patients with type 2 diabetes progressive decline in pancreatic function, the need for strict control of blood glucose levels. Long-term maintenance of optimal blood glucose levels has been shown to reduce the risk of microvascular and macrovascular complications in patients with type 1 and type 2 diabetes. Clinical trials have shown that thiazolidinediones (TZDs) alone or in combination with metformin and sulfonylureas maintain long-term good blood glucose levels. Pioglitazone can reduce long-term cardiovascular morbidity and mortality in patients with type 2 diabetes.