论文部分内容阅读
目的：探讨脉搏波传导速度（Pulse Wave Velocity, PWV）在糖代谢异常患者早期血管病变中的诊断价值。方法选择100例糖调节受损者（IGR）、100例（病程5年以内）的2型糖尿病患者（T2DM），100例正常糖代谢者（NGT），均除外严重的心脑血管疾病。分别检测外周动脉间的脉搏传导速度（PWV），并检测空腹血糖（FPG）、餐后2 h血糖（2hPG）、甘油三酯（TG）、总胆固醇（TC）、等指标，然后对比三组患者的各外周动脉之间的 PWV差异。结果糖调节受损者组、糖尿病患者组和正常糖代谢者对照组的外周动脉PWV之间具有显著差异（P<0.05），其中IGR组（1350±220）cm/s，T2DM组（1780±390）cm/s，NGT组（970±150）cm/s。结论糖尿病患者及糖调节受损患者的外周动脉脉搏传导速度，均明显高于正常糖代谢者。检测脉搏波传导速度，对糖代谢异常患者的血管并发症的早期发现和及时干预，可能发挥重要作用。“,”Objective To explore the diagnostic value of pulse wave velocity in early vascular disease in patients with abnormal glucose metabolism. Method 100 cases with impaired glucose regulation (IGR), 100 cases with type 2 diabetes (suf ered from diabetes within 5 years) were chosen, while 100 normal glucose tolerance persons were chosen as control group.(al of them without serious cardio-cerebra vascular diseases). Pulse wave velocity were measured, and height, weight, blood pressure, fasting plasma glucose(FPG), postprandial blood glucose(2hPG),triglyceride(TG),total cholesterol(TC) of al the cases were tested. Then we contrasted the dif erence pulse wave velocity between the three groups by T test. Results We found it displayed a significant dif erence (P<0.05)in peripheral artery PWV between the impaired glucose regulation group (1350±220cm/s), the type 2 diabetes group (1780±390cm/s),and the normal glucose tolerance group (970±150cm/s). Conclusion Type 2 diabetics and impaired glucose regulation suf ers had significantly higher levels of peripheral artery PWV, compared with normal glucose tolerance group. Pulse wave velocity may play important roles in early finding and timely intervention of vascular complication in patients with disorders of glucose metabolism.