Identification of hedgehog signaling as a potential oncogenic driver in an aggressive subclass of hu

• 作 者: Yang Zhao Li Zhang Yong Zhang
• 机 构: CollegeofLifeScienceandBioengineering,StateKeyLaboratoryofProteomics,CenterforBioinformaticsandCompu
• 出 处: 中国科学:生命科学英文版
• 发表日期: 2019年11期
• 关键词: hepatocellular carcinoma The Cancer Genome ATLAS molecular SUBCLASS Wnt HEDGEHOG
• 基金项目: financial support from the National Key Program for Basic Research of China(2017YFC0906603,2017YFC0908404,2016YFA0501300),the National Natural Science Foundation of China(81530021),the Beijing Municip

Hepatocellular carcinoma(HCC)is a heterogeneous disease and the second most common cause of cancer-related death worldwide.Marked developments in genomic technologies helped scientists to understand the heterogeneity of HCC and identified multiple HCC-rel