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长春新碱(vincristine,VCR)已被广泛应用于恶性肿瘤的化疗30年。由于常规剂量的 VCR 对骨髓的抑制作用较轻,因此常用于联合化疗的各种方案中。由于 VCR 对神经系统的毒性作用临床使用受限。VCR
Vincristine (VCR) has been widely used in cancer chemotherapy for 30 years. Since conventional doses of VCR have less inhibitory effects on bone marrow, they are commonly used in various combinations of chemotherapy. Clinical use is limited due to the toxic effects of VCR on the nervous system. VCR