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人类肿瘤的发展被认为是由于多种基因共同作用的结果,即原癌基因的激活和肿瘤抑制基因的失活,正常人体内存在抑制细胞无限增殖的复杂机制。其中染色体端粒行为及端粒酶表达异常在肿瘤形成中扮演重要角色。一、端粒、端粒酶研究与大肠癌关系1989年耶鲁大学的Mori...
The development of human tumors is thought to be the result of a combination of multiple genes, namely the activation of proto-oncogenes and inactivation of tumor suppressor genes, and the complex mechanisms that inhibit the infinite proliferation of cells in normal humans. Chromosome telomere behavior and abnormal telomerase expression play an important role in tumor formation. One, telomeres, telomerase research and colorectal cancer in 1989 Yale Mori...