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1929年Taylor首先描述了组织学为良性而临床经过为恶性的卵巢肿瘤。1971~1973年FIGO和WHO在国际上公认这种卵巢上皮性肿瘤的特殊类型,称为交界型肿瘤或低度恶性肿瘤。这类肿瘤的特征如下:上皮增生至三个细胞层或形成的上皮胚芽能在囊腔内脱落,细胞异型性、有丝分裂率高和肿瘤有种植的可能,但无间质浸润,若干年后还可复发。因此,提出首次手术治疗的彻底性和辅助治疗的必要性,还应尽可能长期观察。 1966年1月1日~1986年12月31日Erlangen大学妇科医院回顾性检查51例交界型肿瘤,分析治疗时患者的年龄、组织学类型、肿瘤分期和治疗,观察时间为12~251个月(平均114个月)。诊断时
In 1929 Taylor first described histologically benign and clinically malignant ovarian tumors. 1971 ~ 1973 FIGO and WHO in the international community recognized a special type of ovarian epithelial tumor, called borderline or low-grade cancer. The characteristics of these tumors are as follows: Epithelial hyperplasia to the three cell layers or the formation of epithelial germ in the cystic cavity shedding, cell atypia, mitosis rate and the possibility of tumor planting, but no interstitial infiltration, a few years later Recurrence. Therefore, the first time the surgical treatment and the necessity of adjuvant therapy, but also should be observed as long as possible. From January 1, 1966 to December 31, 1986, gynecological hospital of Erlangen University retrospectively examined 51 cases of borderline tumors. The patients’ age, histological type, tumor stage and treatment were analyzed. The observation time ranged from 12 to 251 months (Average 114 months). When diagnosed