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抗菌药物在治疗肠出血性大肠埃希菌(Enterohemorrhagic Escherichia coli,EHEC)感染中的作用存在争议,原因在于其可能导致志贺毒素(Shiga toxin,Stx)产量增高而引起溶血尿毒综合征。但在近期EHEC O104:H4型菌株的暴发流行中,某些患者需要使用抗菌药物治疗。为了解抗菌药物对EHEC O104:H4型菌株产志贺毒素
The role of antibacterials in the treatment of Enterohemorrhagic Escherichia coli (EHEC) infections is controversial as it may lead to an increase in the production of Shiga toxin (Stx) resulting in hemolytic uremic syndrome. However, in the recent outbreak of EHEC O104: H4 strains, certain patients require antimicrobial treatment. To understand antibacterials produce Shiga toxin against EHEC O104: H4 strains