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目的:分析应用腹腔镜实施输卵管造口治疗不孕症并输卵管积液的临床疗效。方法:将60例不孕症并输卵管积液患者根据积液量分为小量组(积液直径<3 cm,患者33例)和大量组(积液直径≥3 cm,患者27例),对比两组的临床治疗效果。结果:两组手术时间、术中出血量及术后下床时间比较未见统计学差异(t=0.012 1,P=0.495 1;t=0.091 1,P=0.463 8;t=-0.394 4,P=0.347 3)。术前两组患者白细胞介素2(IL-2)和白细胞介素10(IL-10)比较未见统计学差异,治疗后两组患者IL-2和IL-10均显著改善,但小量组较大量组改善更为明显(t=-32.029 7,P=0.000 0;t=97.634 9,P=0.000 0)。同时在随访1年的时间内,小量组妊娠率明显高于大量组(χ2=5.725 1,P=0.016 7),且小量组妊娠成功患者的妊娠平均时间为(5.78±1.13)月,明显短于大量组妊娠成功患者的妊娠平均时间(7.22±1.25)月(t=-2.958 4,P=0.003 2)。结论:腹腔镜实施输卵管造口治疗不孕症并小量输卵管积液的疗效明显优于不孕症并大量输卵管积液。
Objective: To analyze the clinical effect of laparoscopic tubal incision in the treatment of infertility and tubal effusion. Methods: Sixty infertility patients with tubal effusion were divided into three groups: small volume group (33 cm in diameter) and large volume group (27 cm in diameter ≥ 3 cm) Compare the clinical treatment effect of two groups. Results: There was no significant difference between the two groups in the operation time, intraoperative blood loss and postoperative ambulation time (t = 0.012 1, P = 0.495 1, t = 0.091 1, P = 0.463 8, t = -0.394 4, P = 0.347 3). There were no significant differences in IL-2 and IL-10 between the two groups before operation, but the levels of IL-2 and IL-10 in the two groups were significantly improved after treatment The improvement in the larger group was more pronounced (t = -32.029 7, P = 0.000 0; t = 97.634 9, P = 0.000 0). At the same time, the pregnancy rate in the small group was significantly higher than that in the large group (χ2 = 5.725 1, P = 0.016 7) during the follow-up period of 1 year. The average pregnancy time in the small group was (5.78 ± 1.13) months, Significantly shorter mean duration of pregnancy (7.22 ± 1.25) months (t = -2.958 4, P = 0.003 2) was found in the pregnant women who were significantly shorter than in the large number of pregnancies. Conclusion: The efficacy of laparoscopic tubal stoma for the treatment of infertility and small amount of tubal effusion is obviously better than that of infertility and tubal effusion.