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目的探讨降钙素原(PCT)在病毒性脑膜炎和细菌性脑膜炎鉴别诊断中的应用价值。方法通过对27例细菌性脑膜炎和32例病毒性脑膜炎患者血清PCT值的检测和比较,从而分析降钙素原在其鉴别诊断中的临床意义。结果细菌性脑膜炎患者血中的PCT平均浓度为37.84 ng/ml,病毒性脑膜炎患者的PCT平均浓度为0.41 ng/ml,两者相比差异有统计学意义(χ2=28.45,P<0.01),特异性分别为100%和96.9%。结论降钙素原对病毒性脑膜炎和细菌性脑膜炎的鉴别诊断具有临床应用价值。
Objective To investigate the value of procalcitonin (PCT) in the differential diagnosis of viral meningitis and bacterial meningitis. Methods The clinical significance of procalcitonin in the differential diagnosis of 27 cases of bacterial meningitis and 32 cases of viral meningitis in patients with PCT detection and comparison. Results The average concentration of PCT in blood of patients with bacterial meningitis was 37.84 ng / ml and that of patients with viral meningitis was 0.41 ng / ml (χ2 = 28.45, P <0.01) ), The specificity was 100% and 96.9% respectively. Conclusions Procalcitonin has clinical value in the differential diagnosis of viral meningitis and bacterial meningitis.