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目的:通过尼莫地平检测脑血管反应性与屏气试验的比较,判断尼莫地平试验的可行性。方法:78例体检者通过经颅多普勒超声,检测静脉泵入尼莫地平和屏气试验2种方法对大脑中动脉平均流速的影响,计算脑血管反应性(尼莫地平试验)和屏气指数(屏气试验)。结果:2例女性被检者因血压下降未完成试验,成功率97.4%。2种方法检测的最大平均流速比较差异无统计学意义,最大与基础平均流速比较差异均有统计学意义。结论:尼莫地平试验能够检测脑血管反应性,安全性高。
OBJECTIVE: To determine the feasibility of nimodipine test by comparing nimodipine to cerebral vascular reactivity with breath-hold test. Methods: 78 patients were examined by transcranial Doppler ultrasound, nimodipine intravenous pump test and breath test two methods on the average velocity of the middle cerebral artery, the calculation of cerebral vascular reactivity (nimodipine test) and the breath hold index (Breath test). Results: Two women were seized due to decreased blood pressure test, the success rate of 97.4%. There was no significant difference in the maximum average flow velocity detected by the two methods, and the difference between maximum and basic average flow velocity was statistically significant. Conclusion: The nimodipine test can detect cerebrovascular reactivity with high safety.