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目的探讨胎盘多肽注射液治疗晚期骨肿瘤的临床疗效。方法选取2007年1月至2013年11月间我院收治的80例骨肿瘤患者,随机分为对照组(单纯化疗组)和观察组(化疗联合胎盘多肽注射液组),每组各40例,观察比较两组患者治疗后生活质量评分(QOL)、免疫功能、体力状况评分(KPS)及不良反应。结果与对照组比较,观察组患者治疗后QOL评分明显升高,CD+3、CD+4、CD+4/CD+8、NK细胞活性明显升高,体力较前明显改善,不良反应程度明显减轻,差异有统计学意义(P<0.05)。结论对于晚期骨肿瘤患者,胎盘多肽注射液能够改善患者生活质量,提高机体免疫力,降低不良反应及程度,值得临床推广。
Objective To investigate the clinical efficacy of placental peptide injection in the treatment of advanced bone tumors. Methods Eighty patients with bone tumor admitted to our hospital from January 2007 to November 2013 were randomly divided into control group (chemotherapy alone group) and observation group (chemotherapy combined with placental peptide injection group), 40 cases in each group The quality of life (QOL), immune function, physical status score (KPS) and adverse reactions were compared between the two groups after treatment. Results Compared with the control group, the QOL score of patients in the observation group was significantly increased after treatment. The activity of CD + 3, CD + 4, CD 4 + CD 8, and NK cells in the observation group were significantly higher than those in the control group. The physical strength was significantly improved and the degree of adverse reactions was significantly higher Reduce, the difference was statistically significant (P <0.05). Conclusion For patients with advanced bone tumors, placental peptide injection can improve the quality of life of patients, improve immunity, reduce adverse reactions and degree, is worth clinical promotion.