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用普通琼脂糖快速电泳法和２，４—二硝基苯肼法分别测定２１例ＡＭＩ患者血清ＣＫ－ＭＭ亚型和ＰＫ的活力，动态观察ＡＭＩ发病后不同时间ＣＫ－ＭＭ亚型和ＰＫ的变化，对比ＣＫ和ＣＫ－ＭＢ，以评价各指标在ＡＭＩ后不同时间的诊断价值。结果：ＡＭＩ发病５ｈ内首次血清ＣＫ－ＭＭ３％高于心绞痛组和对照组，ＭＭ３／ＭＭ１比值高于心绞痛组和对照组（Ｐ＜０．０１）。而同时限测定的ＣＫ、ＣＫ－ＭＢ和ＰＫ与心绞痛组和对照组比较无差异（Ｐ＞０．０５）；梗塞后６ｈ内ＭＭ３／ＭＭ１诊断阳性半天高１９～２４ｈ内ＰＫ和ＣＫ－ＭＢ诊断阳性率最高；３６～７２ｈＣＫ诊断阳性率最高。血清ＣＫ－ＭＭ亚型，尤其是ＭＭ３／ＭＭ１是ＡＭＩ最早、最敏感的生化指标。
The serum CK-MM subtypes and PK activity in 21 patients with AMI were determined by ordinary agarose electrophoresis and 2,4-dinitrophenylhydrazine respectively. The CK-MM subtype and PK at different time after AMI were observed dynamically Changes, CK and CK-MB compared to evaluate the diagnostic value of various indicators at different times after AMI. Results: The first serum CK-MM3% within 5 hours after onset of AMI was higher than that of angina pectoris group and control group, and the ratio of MM3 / MM1 was higher than that of angina pectoris group and control group (P <0.01). However, CK, CK-MB and PK in the same time limit had no difference with those in angina pectoris group and control group (P> 0.05). PK and CK-MB were diagnosed within 6 ~ The highest positive rate; 36 ~ 72hCK diagnosis highest positive rate. Serum CK-MM subtypes, especially MM3 / MM1, are the earliest and most sensitive biochemical markers of AMI.