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作者于1941～1971年间共见到29例青紫型先天心脏病合并中枢神经系统受累的病例,他们自发地发生了中枢神经系统受累的症状,而无其他病因的全身症状可查。最常见的血管病理性损害是大脑静脉的血栓形成。主要的心脏畸型是大血管转位(14例)和法乐氏四联症(12例)。发生脑血管意外时的年龄均在4岁以下,以1岁以内最多见(17例)。 29例中14例在病程中并发或有逐渐加重的偏瘫或半身软弱。9例发病突然。许多病例可追溯出从易兴奋性、呕吐、偏瘫、昏睡、抽风直至昏迷和死亡等的发展过程。12例显示颅压增高的征象。在临终时许多
From 1941 to 1971, the authors observed a total of 29 cases of cyanotic congenital heart disease complicated with central nervous system involvement. They spontaneously developed central nervous system involvement symptoms without systemic manifestations of other causes. The most common vascular pathological damage is thrombosis of the cerebral veins. The major cardiac abnormalities were macrovascular transposition (n = 14) and tetralogy of Fallot (n = 12). Cerebrovascular accident occurred at the age of 4 years of age, the most common within 1 year of age (17 cases). Of the 29 cases, 14 had hemiparesis or half-length weakness during the course of the disease. 9 cases of sudden onset. Many cases can be traced back from the development of excitability, vomiting, hemiplegia, lethargy, aspiration and coma and death. 12 cases showed signs of increased intracranial pressure. Many at deathbed