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自从Robert于1979年首次提出前列腺素(PGs)的“细胞保护作用”以来,PGI_2已被证实对休克、急性胃肠粘膜损害、肝细胞坏死具有保护作用。本实验通过观察外源性前列环素(PGI_2)对缺乏胆碱的乙硫氨酸(CDE)饮食所致小鼠急性坏死性胰腺炎(ANP)时
PGI_2 has been shown to have protective effects against shock, acute gastrointestinal mucosal injury, and hepatocellular necrosis since Robert first proposed “cytoprotection” of prostaglandins (PGs) in 1979. In this study, we observed the effects of exogenous prostacyclin (PGI_2) on mice with acute necrotizing pancreatitis (ANP) induced by a choline-deficient ethionine (CDE) diet