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结核性脑膜炎早期诊断的误诊率高,是多年来的一个难题。该病的病死率高(10％～30％),其主要原因与早期误诊有关,尤其是儿童。有报道儿童的误诊率可高达40％以上。由于诊断不及时,延误治疗常导致严重的并发症和后遗症,病死率也增高。多年来,国内外学者为减少误诊,致力于探索简便、快速的早期实验诊断方法。荧光素钠渗透试验(FST)在国内外虽已有报道,但有关小儿的报道尚少。本文对我院1990年1月～1991年8月住院的104例患儿进行了FST,以观察FST法诊断结核性脑膜炎和判断治疗效果方面的应用价值。
The high misdiagnosis rate of early diagnosis of tuberculous meningitis is a problem for many years. The case fatality rate (10% to 30%), the main reason for the early misdiagnosis, especially children. It has been reported that the misdiagnosis rate of children can be as high as 40% or more. As the diagnosis is not timely, delayed treatment often leads to serious complications and sequelae, the case fatality rate also increased. Over the years, domestic and foreign scholars to reduce misdiagnosis, dedicated to exploring the simple, rapid early experimental diagnosis. Sodium fluorescein penetration test (FST) has been reported at home and abroad, but little is reported in children. In this paper, our hospital from January 1990 to August 1991 hospitalized 104 cases of FST were performed to observe the FST method of diagnosis of tuberculous meningitis and determine the therapeutic effect of the application value.