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研究肝硬化门脉高压合并食管静脉曲张患者行硬化、套扎治疗对食管测压的影响。硬化与套扎治疗组均于治疗前及治疗后各测压一次。结果显示 :①硬化剂治疗后 ,食管下端括约肌 (LES)静息压及松弛压力降低 ,松弛率升高 ,松弛持续时间缩短 ;套扎治疗仅对LES静息压有影响。②硬化剂治疗使治疗部位及其以下食管的蠕动波幅值下降 ,蠕动持续时间延长 ,蠕动波速度加快 ;套扎治疗使治疗部位及其以下食管的蠕动持续时间缩短 ,异常蠕动性收缩增加。提示硬化治疗后应使用既能降低胃酸酸碱度 ,又能增加LES压力的抗酸药物 ,而套扎治疗后应使用胃动力药物。
To study the effects of sclerosis and ligation on esophageal varices in patients with cirrhosis and portal hypertension combined with esophageal varices. Sclerosis and ligation treatment group before and after treatment, each manometry. The results showed that: (1) Resting pressure and relaxation pressure of lower esophageal sphincter (LES) decreased and the relaxation rate increased and the duration of relaxation shortened after sclerotherapy; Ligation only affected resting pressure of LES. ② The sclerotherapy treatment reduced the amplitude of peristaltic wave amplitude of the treatment site and the following esophagus, prolonged the duration of peristalsis and accelerated the wave of peristaltic wave; the duration of peristalsis of the treatment site and its lower esophagus was shortened and the abnormal peristalsis contracted. Tip after sclerotherapy should be used to reduce both acid-base pH, but also increase the pressure of anti-acid LES drugs, and ligation of gastric motility drugs should be used.